Example sentences for: acly

How can you use “acly” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although ACC was not regulated at the transcriptional level, cytoplasmic citrate (generated from the Acly reaction) is an allosteric activator of ACC, so less cytoplasmic citrate would lead to less activation of ACC [ 45 ] . Transcript levels of hepatic acetyl CoA synthetase 1 AMP forming (acetate:CoA ligase AMP forming; Acas1) were consistently down regulated by LC-PUFA (-2.

  • It is intriguing that, in general, both Acly and Fasn were more strongly down regulated with the combination diet than the individual LC-PUFA.

  • In the cytoplasm, FA synthesis is controlled via Acly, acetyl CoA carboxylase (ACC), and Fasn.

  • It is not clear why FUNG did not also up regulate transcripts, as LC-PUFA are generally reported to up regulate this isomerase [ 51 ] . The present data generally suggest LC-PUFA increased FA oxidation by down regulating Acly; and up regulating Cpt-1 and -2, Ech1 and Acadm.

  • As described above, Acly expression (and possibly ACC activity) was significantly down regulated by LC-PUFAs, likely leading to less FA synthesis.


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