Example sentences for: abnormality

How can you use “abnormality” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Fabry disease is an X-linked disorder resulting in reduced activity of the lysosomal enzyme α-galactosidase A [ 1 2 ] . This results in the systemic accumulation of D-galatosyl conjugates, particularly globotriosylceramide (Gb3) [ 3 4 ] . Although the disorder is heterogeneous, patients suffer renal, cardiovascular and cerebrovascular complications [ 4 ] . Enzyme replacement therapy has recently shown to have an effect on resting cerebral blood flow abnormalities and on other organ systems functions [ 5 6 ] . In the cerebrovascular system there is an increased incidence of stroke together with vessel ectasia [ 7 ] . This may be related to the progressive accumulation of storage material in the cerebral vessel or possibly, may be due to an abnormality of vessel function [ 8 9 ] . The cerebrovascular complications are distributed predominantly in the posterior circulation with a progressive increase over time in the posterior distribution of small vessel disease as found on T 2 -weighted images or fluid attenuated inversion recovery (FLAIR) MR [ 7 10 11 ] . It likely that such high signal lesions on MR images represent ischemic small vessel disease, however, there are no neuropathological-radiological correlative studies confirming this assumption.

  • A core group of kids do have a distinct attention abnormality, but Ritalin worked so well--it can reduce distractibility even in perfectly normal children--that now almost any "difficult" child is considered for the diagnosis and drug.

  • The first factor is believed to cause the disorder and is most likely a structural or functional central nervous system (CNS) abnormality, whereas the second factor reinforces the first one, especially through avoidance learning.

  • There is enormous epidemiological interest in establishing the link of ATM gene abnormality with cancer risk, since the percentage of the ATM heterozygotes is high, and estimated to represent 1.5% of total population.

  • None was known to have pre-existing isolated IgA deficiency or other abnormality of immunity.


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