Example sentences for: abnormality

How can you use “abnormality” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Following ERT, this resting rCBF abnormality was reversed [ 5 ] .

  • Of these 14 patients, the highest degree of abnormality in 4 was metaplasia, in 4 dysplasia, in 3 CIS, in 1 invasive squamous cell carcinoma, and in 2 invasive adenocarcinoma.

  • Indeed, alterations in AVP regulation and secretion are thought to be one possible biochemical abnormality in patients with Obsessive Compulsive Disorder (OCD) [ 15 16 17 18 ] . This disorder is characterized by sudden, recurrent thoughts or images that intrude into consciousness (obsessions) driving stereotyped acts that the person feels compelled to perform (compulsions) [ 19 ] . Interestingly, patients with OCD show elevated basal levels of AVP in the cerebrospinal fluid and exaggerated plasma levels of AVP in response to hypertonic challenge [ 16 ] . Many patients with anorexia nervosa and bulimia nervosa, both compulsive eating disorders, have abnormal levels of AVP in the cerebrospinal fluid and plasma [ 15 17 ] . Pediatric patients with severe OCD have low levels of AVP in cerebrospinal fluid, while a subgroup of pediatric patients with compulsive checking rituals has elevated AVP levels [ 18 ] . Hence, there are many clinical examples of compulsive behavior associated with a perturbation in the AVP system.

  • During the last trimester of human pregnancy, the placenta may exhibit pronounced abnormality associated with generalized villous degeneration, often called placental aging or senescence [ 22 23 24 27 43 44 45 ] . We have recently shown that placental abnormality is associated with the diminution of Thy-1 differentiation protein immunostaining in the villous core and less or more pronounced dilatation of villous sinusoids.

  • The multicentre cohort study of prophylactic mefloquine use should be questionnaire-based, and should enquire specifically into the major risk factors (alcohol intake during travel, hydration status, use of hormonal contraception and recreational drugs, other potentially hepatotoxic or thyrotoxic drugs, previous history of proven or suspected liver and/or thyroid abnormality) that we have proposed.


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