Words similar to abcg

Example sentences for: abcg

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Abcg8 mRNA could be important, if message stability were affected.
The identified G1754T (Gly583Cys) missense mutation of the Abcg5 generates loss of a restriction site for Hae III after PCR amplification of exon 12, and this allowed a PCR-RFLP assay to further confirm the detected change (Figure 5B).
All of these strains are homozygous mutant for Gly583Cys in sterolin-1, encoded by Abcg5 . This mutation is not present in rats that were not sitosterolemic, even though one of these was hypertensive (the GH rat).
Rat cDNAs for Abcg5 and Abcg8 were identified previously by amplification of these sequences from a Sprague Dawley rat enterocyte cDNA library, using primers located in areas conserved between mouse and human (Genbank AF312714 and AF351785 respectively).
The GH rat was selected for systolic hypertension that increased with successive generations and maintained through filial matings [ 45 ] . In view of this, the Gly583Cys missense mutation of Abcg5 might result from occurrence of a de novo mutation during breeding at the stage of developing inbred WKY strains and propagated into the SHR and SHRSP lines.