Example sentences for: abcg

How can you use “abcg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Abcg8 . However, only one non-synonymous nucleotide change, G1754T, resulting in a conservative cysteine substitution for glycine at amino acid 583 (Gly583Cys) in sterolin-1 was identified (Fig.

  • ABCG5 and ABCG8 are two genes located adjacently in a head-to-head configuration on human chromosome 2p21, encoding for two half-transporters, sterolin 1 and sterolin 2 respectively [ 9 10 12 ] . Mutations in either of these genes causes sitosterolemia, characterized by hyperabsorption of phytosterols, reduced excretion of sterols into the bile and very elevated levels of plasma plant sterol levels.

  • Additionally, while screening an enterocyte cDNA library for full length cDNAs using PCR, we consistently amplified two DNA products when using Abcg8 primers flanking exon 2; one of the expected size, and another very low copy product ~60 bases larger.

  • However, a literature search revealed that a few strains of rats, studied primarily for investigation of hypertension and stroke, have been reported to be sitosterolemic as well [ 15 16 ] . We hypothesised that these rat strains may be mutated in either Abcg5 or Abcg8 . Tissue (and plasma) plant sterol levels in the Wistar Kyoto (WKY) rat, the spontaneously hypertensive rat (SHR) and the stroke-prone spontaneously hypertensive rat (SHRSP) were significantly higher than in Wistar and WKA rats fed either a regular chow diet or diets that have higher plant sterols and these were correlated with increased death, or red cell hemolysis etc. [ 15 16 17 18 19 20 21 22 ] . Dietary sterol absorption rates were increased, with a decrease in sterol excretion [ 16 ] , characteristics similar to that observed in sitosterolemic patients.

  • Using a more sensitive RT-PCR analyses of RNA obtained from different tissues confirmed that rat Abcg5 and Abcg8 genes were expressed in both in the liver and small intestine, with a low level of expression in the colon (Fig.


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