Words similar to abcg

Example sentences for: abcg

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Both of these methods gave consistent results and indicated that expression of Abcg5 was increased approximately 2-fold in the SHR but not the Wistar or SD (Fig.
Expression levels of Abcg5 and Abcg8 in these rat strains were examined in two ways.
Additionally, while screening an enterocyte cDNA library for full length cDNAs using PCR, we consistently amplified two DNA products when using Abcg8 primers flanking exon 2; one of the expected size, and another very low copy product ~60 bases larger.
Interestingly, a similar whole-body accumulation of plant sterols, less severe than in human sitosterolemia, has been reported recently in SHR, SHRSP and WKY rats, but not in the other genetically related rat strains, such as SD, Wistar and WKA rats [ 16 ] . These rats exhibit defects at two levels: increased absorption of sterols (plant and animal) at the intestinal level and decreased excretion of sterols into bile [ 16 ] . The higher sterol absorption in the intestine and the lower biliary excretion of plant sterols in these rat strains led us to hypothesise that Abcg5 or Abcg8 gene mutations may be responsible for the sitosterolemia observed in these hypertensive rats.
We interrogated this region for genetic variations and found a correlation between sitosterolemic strains and a missense mutation in Abcg5 .