Example sentences for: prostanoid

How can you use “prostanoid” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Gonadotropin-induced progesterone production is attenuated by PGF 2α treatment, but this prostanoid does not activate apoptosis of bovine steroidogenic cells in vitro [ 8 ] . These findings helped develop the concept that additional factors, such as immune cells [ 5 6 7 ] or cytokines [ 7 8 ] , contribute to the luteolytic process.

  • The relative position of the intron to the coding regions is also identical to that found in the human TP, the human and mouse DP, and the human EP 1 gene [ 2 ] . This provides further evidence that the prostanoid receptor family arose from a common ancestral gene.

  • A prolonged half time to recovery has been associated with a decreased nitric oxide and prostanoid production [ 8 ] and a loss of endothelium dependent vasodilation [ 9 ] . Reduced vascular reactivity is associated with many diseases that are associated with aging [ 15 16 17 ] . We did not find activity effects on half time to recovery.

  • Many cell types, including lung fibroblasts, contain cyclooxygenase (COX), a proximal enzyme in prostanoid production, and can generate prostanoids [ 19 ] . It has been previously reported that IPF lung fibroblasts have decreased COX-2 expression compared to normal lung fibroblasts and, hence, have decreased PGE 2 production [ 12 20 21 ] . Because of these findings and the fact that PGs are important fibroblast regulators, we sought to investigate whether abnormalities in COX-2 expression could be associated with an altered balance between profibrotic and antifibrotic PGs.


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