Example sentences for: peptide-based

How can you use “peptide-based” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Multiple antigen peptide vaccines can also be designed to contain T and B epitope regions from numerous protein antigens derived from a complex infectious agent which could therefore confer broad protection without the potential dangers of an attenuated whole organism vaccine [ 16 ] . However, it is of note that occasionally a well-designed peptide-based vaccine can elicit strong antibody responses to the synthetic immunogen that do not confer protection from the parasite to which they were originally designed [ 23 ] . This may be due to either the induction of an inappropriate antibody isotype in the mouse strain used, or to an inadequate overall response.

  • DNA- and peptide-based vaccines have become popular due to the comparative ease of construction, the circumvention of potential safety issues around attenuated organisms, and for their potentially enhanced immunogenicity compared to heat-killed and subunit vaccines [ 20 21 22 ] . DNA vaccines have the added attraction of efficiently priming both humoral and cytotoxic cell responses, a property largely lacking in subunit and attenuated organism vaccines.

  • Pyochelin from Pseudomonas aeruginosa exemplifies an iron siderophore whose peptide-based synthesis depends on CoA-activated salicylate (closely related to anthranilate) as a starter unit [ 36].


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