Example sentences for: paraplegin

How can you use “paraplegin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Some cases of HSP result from mutations in the gene for paraplegin, a nuclear-encoded mitochondrial metalloprotease, including: a 2 bp deletion at position 784, which causes a frameshift that eliminates 60% of the protein; and an adenine insertion at position 2,228 of the paraplegin cDNA, which creates a frameshift resulting in truncation of the last 57 residues of this 795-residue protein [ 37].

  • No missense mutations have been found in human paraplegin to date.

  • Paraplegin homologs, analogous to the yeast paralogs Afg3p, Rca1p and Yme1p, must almost certainly exist, and human prohibitins may be expected as well.


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