Example sentences for: overproduction

How can you use “overproduction” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Immunohistochemical analysis indicated a significant overproduction of TGF-β 1 , PDGF-A, and PDGF-B in the MCMV induced intimal lesion (Fig.

  • To further explore the apparent change in promoter specificity of this polymerase, we carried out an additional screen in which R3-17 was again cloned adjacent to the library of promoter mutations, and replica-plated colonies that grew poorly or not at all upon IPTG induction (indicating polymerase overproduction) were picked and sequenced.

  • Consistent with this idea, E2F overproduction can induce apoptosis [ 12 ] [ 13 ] . Furthermore, cell cycle specific destruction of E2F was suggested by the finding that E2F protein becomes undetectable in the synchronised S phase cells of the morphogenetic furrow of the eye imaginal disc [ 12 ] . Our double labelling analysis extended this finding to the asynchronously cycling cells of the wing imaginal disc and demonstrated that E2F is rapidly degraded prior to significant DNA replication.

  • This highlights the importance of macrophages in the production of TNF, supported by current hypotheses on the pivotal role of this cell type in TNF overproduction in autoimmune diseases [ 39 ] . Thus, our findings suggest that TTP serves an entirely different role in other leukocytes, relative to their role in regulating cytokine production by macrophages, and that TNF production is not simply regulated by TTP.

  • GC's induce negative feedback regulation on pituitary ACTH production, as a mechanism for protecting against GC overproduction.


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