Example sentences for: originate

How can you use “originate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • TSP-1 is a homotrimeric multidomain glycoprotein synthesized and secreted by numerous cell types, including platelets, vascular smooth muscle cells and keratinocytes [ 4 ] . Due to its interaction with a wide variety of proteins, TSP-1 has been implicated in a number of biological processes including coagulation, cell adhesion, the modulation of cell-cell and cell-matrix interactions, control of tumor growth and metastasis, and angiogenesis [ 10 ] . Inhibition of tumor cell proliferation has been achieved in vivo by systemic treatment with TSP-1 peptide mimetics [ 11 ] , but a correlation between primary tumor TSP-1 expression and poor prognosis has not been clearly established [ 12 ] . While there are reports that these molecules can originate from tumor cells [ 13 ] , the majority of reports have suggested that the major source of both TSP-1 and OPN is tumor-associated stroma [ 14 ] or infiltrating macrophages and lymphocytes [ 15 ] .

  • It is important to note that pseudogenes are common in the human genome, and are thought to largely originate from gene duplication or retrotransposition [ 27].

  • For that reason neither backward nor forward elimination of variables was carried out in these analyses; the AORs originate from the initial complete model.

  • In contrast, antisense transcripts that originate from the same genomic region (but with opposing orientation) have, by virtue of their common but complementary origin, the potential to form long perfect duplexes.

  • Did the C. psittaci trpoperon originate by lateral gene transfer?


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