Example sentences for: orderly

How can you use “orderly” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • ' If we were to construct a new vocabulary from scratch from the point of view of an extremely orderly, but over-zealous, cataloguer, we might have as the first two words in our dictionary AAAA and AAAB.

  • Fas contains a single transmembrane domain and belongs to the tumor necrosis factor (TNF)/nerve growth factor family [ 8 ] . FasL contains a single transmembrane domain and is also a member of the same TNF family [ 9 ] . A soluble form of FasL has been described, but appears to be less capable of inducing apoptosis, when compared with the bound form [ 10 11 ] . The binding of FasL with Fas initiates receptor oligomerization, which recruits Fas-associated death domain (FADD) [ 12 ] . FADD binds procaspase-8 and permits activation of caspase-8 through self-cleavage [ 13 ] . Caspase-8 activates the effector caspases, which commits the cell to the orderly process of apoptosis [ 14 15 ] . In addition, caspase-8 cleaves Bcl-2-interactive-death-agonist (Bid) [ 16 ] . Truncated Bid localizes to the mitochondria and promotes cytochrome c release; this process also serves as a major apoptotic-signaling pathway for Fas [ 16 17 18 ] . Depending upon the amount of caspase-8 that is activated, the predominant pathway can be either Bid cleavage with subsequent mitochondrial release of cytochrome c or activation of the effector caspase pathway [ 18 ] . Resident cells of the kidney express both Fas and FasL and Fas/FasL signaling is functional in these cells [ 19 20 21 22 23 24 ] . A recent review by Ortiz and associates [ 25 ] noted that the combined literature demonstrating participation of Fas/FasL pathway in renal injury essentially fulfilled Koch's postulates.

  • Each company had a plan for eventually achieving a quantum leap in the performance of its products and had established an orderly, phased process for getting there, by undertaking continuous product improvements as resources became available.

  • He would take notes on his yellow pad and sum up the sense of our meetings in an orderly manner, as he had always done.

  • In this view, Delta-Notch signaling diversifies neural cell fate by guiding the orderly, and prolonged, transition from neural precursor cells to specified cells.


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