Words similar to igf-ir

Example sentences for: igf-ir

How can you use “igf-ir” in a sentence? Here are some example sentences to help you improve your vocabulary:

The tumors from U87 cells infected with the IGF-IR virus are also very cellular, but the cells have larger nuclei (left panel) and have completely invaded the capsule (right panel).
The tumors from U87 cells infected with the kinase inactive IGF-IR are less cellular with larger areas of stroma (left panel).
We have previously demonstrated the overexpression and hormone-independent activation of the IGF-IR in primary breast cancers [ 42 ] . Similar overexpression of the IGF-IR and the ligands IGF-I and IGF-II have been seen in human gliomas and astrocytomas [ 43 44 45 46 ] . Because of the important role for the IGF-IR in cell survival, we investigated whether a dominant negative IGF-IR could inhibit growth of the U87 glioma.
There is also evidence implicating the IGF-IR in metastasis.
WT-infected cells gave the largest tumors in both experiments demonstrating that overexpression of the IGF-IR in a malignant cell can enhance tumor formation as we observed for the CHO cells.