Example sentences for: bcr

How can you use “bcr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Remarkably, WT Btk:ER induced apoptosis to a similar extent to that seen with BCR cross-linking (Fig 3C), despite the fact that PLCγ2 phosphorylation, calcium mobilization, ERK and JNK were relatively weakly activated (Figs 2, 3A,B).

  • CD5 has been shown to be physically associated with the T cell receptor (TCR)/CD3 complex in T cells and with B cell receptor (BCR) in B-1a cells [ 11, 12, 13].

  • Btk is thought to be activated upon BCR cross-linking by a two-step mechanism involving phosphatidylinositol (PI) 3-kinase and the Src family PTK Lyn (reviewed in references [ 4, 5, 6]).

  • Although the basal levels of Syk activity were elevated in clones that expressed the (K395A/3F)Syk molecule, the cells were still responsive to BCR signaling.

  • Previous studies have shown that DT40 cells deficient for Btk and PLCγ2 have similar BCR signaling defects.


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