Example sentences for: aldehyde

How can you use “aldehyde” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The order of addition in the assay was as follows: buffer; pyrazole; NAD; ALDH (10 mU mouse liver ALDH1A1; 5 mU human erythrocyte ALDH1A1; or HL-60 cell extract); inhibitor (if any); and lastly, the aldehyde substrate.

  • Retinoids are found in a variety of chemical oxidation states, including alcohol, aldehyde, ester, and carboxylic acid functionalities.

  • Several of the differentially expressed genes, including aldo-keto reductase 1C1 ( AKR1C1 ), aldehyde dehydrogenase 1A1 ( ALDH1A1 ), and alcohol dehydrogenase 1B ( ADH1B ), function in sex steroid and retinoic acid metabolism (Figure 2).

  • MG-132 is a peptide aldehyde that inhibits ubiquitin-mediated proteolysis by binding to and inactivating 20S and 26S proteasomes [ 49 62 ] . Although 1-10 μM MG-132 inhibited first polar body extrusion in rat oocytes, its activity is reversible [ 42 ] . We conducted preliminary experiments to obtain a MG-132 dose range that would transiently perturb or inhibit OM during meiosis I while enabling oocytes to complete OM following washing out of the compound.

  • In one report, ALDH1A1 protein was not detected by Western blot, but enzyme activity was detected using flow cytometry and a fluorescent aldehyde substrate [ 5 ] . In a second study, ALDH1A1 protein was detected using an ELISA assay and activity was detected using aldophosphamide as substrate [ 31 ] . In these two studies, designed to look at the relationship of ALDH1A1 activity to antitumor drug resistance, the levels of ALDH1A1 were low in HL-60 compared to other cell types, corresponding to the sensitivity of HL-60 cells to oxazaphosphorines.


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