Example sentences for: acr

How can you use “acr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • At the completion of the year of observation, patients who were diagnosed as having RA had all met the 1987 American College of Rheumatology (ACR) criteria [ 27] on at least one visit.

  • The inability of rhIL-11 to bring about a statistically significant improvement in the ACR 20% criteria may also be the result of an inability of rhIL-11 to stimulate the synthesis of acute-phase proteins, of the significant clinical response of several placebo-treated patients, or of a lack of adequate power of the study to show efficacy.

  • The Arr2 gene (or ACR2 [ 24 ] ) has been identified as coding for a protein necessary for arsenate resistance in yeast, and appears to have some homology to prokaryotic arsC genes.

  • E174 in ACR3 and S218 in ACR4 are required for catalytic function [ 12 ] . Substitution of H59 in ACR1 converted CD39 into an ADPase in a quaternary structure dependent manner [ 13 ] . Mutation of W187A in ACR3 affected CD39 folding and translocation, while mutation of W459A in ACR5 increased ATPase activity but diminished ADPase activity [ 14 ] . Mutations of D62 and G64 of ACR1 and D219 and G221 of ACR4 demonstrated that the nucleotide phosphate binding domains of NTPDases are similar to those present in the actin/heat shock protein/sugar kinase superfamily [ 15 ] . These results suggest that the conserved residues of the ACR1 to 5 regions are involved in the catalytic mechanism of CD39.

  • Figure 1describes the data using the 20% ACR criteria for response at the various doses or schedules tested.


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