Example sentences for: acr

How can you use “acr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Figure 1describes the data using the 20% ACR criteria for response at the various doses or schedules tested.

  • Except for the tender-joint count, none of the observed disease activities was statistically different from placebo according to the ACR criteria at the 20% improvement level.

  • The endpoint used to characterize clinical activity was the proportion of patients whose disease improved according to the 20% ACR criteria [ 16].

  • E174 in ACR3 and S218 in ACR4 are required for catalytic function [ 12 ] . Substitution of H59 in ACR1 converted CD39 into an ADPase in a quaternary structure dependent manner [ 13 ] . Mutation of W187A in ACR3 affected CD39 folding and translocation, while mutation of W459A in ACR5 increased ATPase activity but diminished ADPase activity [ 14 ] . Mutations of D62 and G64 of ACR1 and D219 and G221 of ACR4 demonstrated that the nucleotide phosphate binding domains of NTPDases are similar to those present in the actin/heat shock protein/sugar kinase superfamily [ 15 ] . These results suggest that the conserved residues of the ACR1 to 5 regions are involved in the catalytic mechanism of CD39.

  • Of note, a large epidemiologic study of patients with early inflammatory arthritis found that the proportion of patients who met the ACR criteria increased if the criteria were applied cumulatively over a 5 year period [ 29].

How many words do you know? Try our free vocabulary size test!


Search for example sentences

Loading Loading...