Words similar to abp
Example sentences for: abp
How can you use “abp” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our data indicate that the presence of greater than physiological concentration of ABP in the mouse testis has a biphasic effect on the frequency of apoptosis in germ cells.
Apoptotic cells were identified by the TdT-mediated dUTP-biotin nick end labeling (TUNEL) method and detected either by flow cytometry [ 27 ] or by light microscopy in histological sections [ 28 ] . The results indicate that transgenic ABP alters the rate of testicular germ cell apoptosis throughout life, but it is most likely to cause its germ-cell depleting effect by promoting germ cell apoptosis during the critical pre-pubertal period ("puberty" in laboratory rodents occurs at 50-60 days of life and is defined as the first appearance of spermatozoa in the tail of the epididymis [ 29 30 ] ).
The presence of increased numbers of ABP-containing germ cells in the testes of ABP-TG mice [ 26 ] and immunocytochemical observations of intense ABP immunoreactivity found in and around all types of germ cells in ABP-TG mice [ 25 ] support a possible direct involvement of ABP in the testicular impairment seen in the ABP-TG mice.
In conclusion, our data suggest that the presence of high concentrations of ABP in the mouse seminiferous tubules results in a dramatically increased wave of germ cell apoptosis during the pre-pubertal period.
The late stages of spermatogenesis (spermiogenesis) were extensively studied for the possible direct effects of ABP [ 16 17 42 43 44 45 ] . In these studies, however, ABP (at least at physiological concentrations) appeared to be supportive, rather than detrimental, to spermatogenesis.
Loading...