Example sentences for: pedf

How can you use “pedf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The data revealed that inhibition of sulfation of GAGs reduced the PEDF binding to cell-surface receptors of Y-79 cells, with about 20% of specific inhibition.

  • The soluble dialysate was mixed with PEDF-resin (6 mg PEDF/ml resin) at a 2:1 volume-to-volume ratio and incubated at 4°C with gentle rocking for 16 h.

  • The differentiation and survival of cells in vivo may be regulated not only by the expression of PEDF and its receptor but also by the temporal and spatial expression of GAGs.

  • Cell-associated HS proteoglycans can undergo regulated shedding from the membrane into the soluble extracellular matrix or culturing medium converting the membrane anchored molecules into soluble effectors [ 1 2 ] . In the conditioned media of all the tested batches of retinoblastoma cells, we detected heparin and HS with binding affinity for PEDF.

  • The fact that the binding of PEDF to cell surfaces decreases with heparin/HS depletion, implies that heparin/HS molecules might act as cofactors for PEDF-receptor interactions.


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