Example sentences for: pedf

How can you use “pedf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The primary consequence of reducing the heparin/HS and its sulfation was to minimize a binding site required for PEDF activity.

  • The binding of GAGs to PEDF that modulate the binding of these factors to its receptor opens also the possibility that different GAGs may modulate differently the affinity of PEDF for its receptors, by increasing or even decreasing it in some cases.

  • Cell-associated HS proteoglycans can undergo regulated shedding from the membrane into the soluble extracellular matrix or culturing medium converting the membrane anchored molecules into soluble effectors [ 1 2 ] . In the conditioned media of all the tested batches of retinoblastoma cells, we detected heparin and HS with binding affinity for PEDF.

  • Specific retention, termed PEDF bound, was calculated by subtracting the retention in defined media from that in CM.

  • The fact that the binding of PEDF to cell surfaces decreases with heparin/HS depletion, implies that heparin/HS molecules might act as cofactors for PEDF-receptor interactions.


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