Example sentences for: pdgfr

How can you use “pdgfr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, C6 glioma cells express additional RTKs including insulin (IR) and platelet-derived growth factor (PDGFR) receptors.

  • PDGFR expression in lung cancer

  • Gleevec was designed to inhibit the BCR-ABL tyrosine kinase, and it cross-reacts with c-kit and PDGFR [ 5 ] . In non-small cell lung cancer, BCR-ABL expression has never been reported, and it is unlikely that BCR-ABL fusion protein plays any role in lung cancer.

  • However, neither of these proteins has been reported to act as a surrogate scaffold during ERK activation by non-opioid GPCRs [ 27 ] . In the present report, DSLET-mediated ERK phosphorylation was unaltered by the presence of the IR or PDGFR antagonists, HNMPA-(AM) 3 and tyrosphostin 9, respectively.

  • Since it has been reported that Gleevec can inhibit the function of PDGFR under the cell culture conditions, it is likely that Gleevec exerts its inhibitory effects on A549 lung cancer cells through inhibiting the PDGFR function.


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