Example sentences for: pdgf

How can you use “pdgf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Growth factors TGF-β, and PDGF are contributing factors in vascular diseases.

  • Gleevec has been demonstrated to inhibit the growth and proliferation of GIST, and induce complete or partial clinical remission in GIST patients [ 6 7 ] . Recently Gleevec was showed to inhibit the growth of dermatofibrosarcma protuberans (DFSP) through inhibiting the PDGF receptor [ 8 9 ] .

  • The cells stimulated with PDGF (2 ng/ml PDGF-BB) received the growth factor 10 min before collecting the cells for lysis, while the other samples received no growth factor or serum.

  • The elevated expression of PDGF in our model is also significant since the expression of these growth factors by endothelial cells can be induced by direct immune cell - endothelial cell interaction, promoting smooth muscle cell migration and proliferation in atherosclerosis [ 39 ] . CMV, as well as other viruses, induces expression of a number of cytokines and growth factors in cells in vitro, including TGF-β, a profibrogenic cytokine [ 40 41 ] . MCP-1 is a member of the β-chemokine (C-C) family [ 42 ] and this chemokine has been implicated in pathogenesis of SSc [ 43 ] . Our results (Fig.

  • The dependence of this increased turnover on phosphorylation of Rlk suggests that a phosphotyrosine-dependent association with another molecule may be required for this process, reminiscent of the increased degradation of the PDGF receptor and Syk caused by association with the ring-finger protein Cbl [ 47, 48, 49] or the Lck-dependent degradation of the TCR [ 50].


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