Example sentences for: pathologic

How can you use “pathologic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A larger number of animals would allow for statistical analysis of pathologic findings such as activated fibroblasts by depth and thickness of newly formed extracellular matrix between experimental and control eyes.

  • It has been suggested that pathologic activation of the mucosal immune system in response to antigens is a key factor in the pathogenesis of IBD.

  • Further understanding the down-stream signaling events in such interaction will provide new insights into the mechanisms underlying normal and pathologic growth of prostate cells, and will facilitate the use of retinoid analogs in the prevention or treatment of such diseases as prostate cancer.

  • Stimulation of RAR α and γ mRNA in LNCaP cells by T differed from that in normal rat prostate and non-tumorigenic rat prostate epithelial cells (NRP-152), but was comparable to that in tumorigenic rat prostate epithelial cells (NRP-154) [ 13 14 ] . In cervical carcinoma cells, the RAR β gene was abnormally down-regulated by RA [ 36 ] . In ER positive human breast cancer cells, RAR α mRNA was also up-regulated by estrogen [ 16 ] . Thus, T stimulation of RAR mRNAs in LNCaP cells could be related to the pathologic state of the cells.

  • Previous studies relating gene expression to pathologic or tissue data have evaluated qualitative tissue information only [ 8 9 ] , or focused on visually identified tissue subareas or specific cells isolated by by laser microdissection (LMD) [ 10 11 12 ] . In LMD, specific cells from a sample are collected by interactively defining areas of interest in a microscope image, which are excised by a laser for subsequent gene-expression analysis.


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