Example sentences for: parp

How can you use “parp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Interestingly, cleavage and inactivation of PARP was noted only at 3 h after STS treatment in BRCA1wt cells.

  • Instead, this amino-terminal mutation favored elevated caspase 3 levels that subsequently facilitated enhanced apoptosis by inactivating the caspase-dependent DNA repair proteins PARP and by inactivating DFF45, an inhibitor of the caspase-dependent DNase, DFF40.

  • PARP (110 kDa protein) was selected as a positive control to monitor the cleavage of proteins during apoptosis and necrosis because its cleavage products in Jurkat cells undergoing apoptosis (89 kDa) and undergoing necrosis (60 and 50 kDa) are well established [ 20 24 30 ] .

  • AGA = anti-Golgi complex autoantibodies; H 2 O 2 = hydrogen peroxide; PARP = polyADP-ribose polymerase; PBS = phosphate-buffered saline; STS = staurosporine; zVAD-fmk = benzylocarbonyl-Val-Ala-Asp-fluromethylketone.

  • In the present study, Jurkat cells were relatively sensitive to the treatment with STS such that the kinetics of degradation of different golgins relative to that of PARP could not be accurately differentiated.


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