Words similar to paralogs
Example sentences for: paralogs
How can you use “paralogs” in a sentence? Here are some example sentences to help you improve your vocabulary:
First, some of the many-to-one associations are due to sequence clusters that contain mistakenly grouped similar sequences from closely related genes (paralogs).
In an attempt to isolate the effect of duplication per se on purifying selection, we analyzed paralogs and orthologs that appeared to encode proteins with similar functions, namely secreted and membrane proteins that were identified by signal peptide and transmembrane helix prediction.
In the remaining triplets, which consisted of an ortholog and two paralogs, p -distances P OP1 , P OP2 and P PP for ortholog-paralog 1, ortholog-paralog 2, and paralog-paralog pairs, respectively, were calculated from the multiple alignment.
Each of these differences in the functional composition of the sets of paralogs and unduplicated genes were statistically highly significant (p < 0.0001, χ 2test).
Unexpectedly, the Anopheles genome contains only four members of this subfamily, and all are located in a single cluster on 2L (Figure 7b); the same four members were identifiable in the unassembled genomic sequence of Apis [ 48 ] . The simplest scenario is that members of the K box-family have undergone radical duplication and dispersal about the genome in Drosophila . This is consistent with the finding that the remaining members of the K-box family [ 47 ] , including mir-11 , the three mir-6 paralogs and the K-box-antisense gene mir-5 , are similarly absent from both Anopheles and Apis . However, one new putative member of the K-box family (2R:4681879) was identified by miRseeker, and it has been conserved in all four sequenced insect genomes.
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