Example sentences for: palmitoylation

How can you use “palmitoylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • sα i2 may fail to undergo palmitoylation because it is not stable long enough for post-translational palmitoylation to occur or because it fails to reach a PM site of palmitoylation.

  • Myristoylation occurs co-translationally at the extreme N-terminal glycine, while palmitoylation occurs post-translationally at a cysteine immediately after the myristoylated glycine [ 15 ] . The subcellular site where palmitoylation occurs has not been well defined, although in one model palmitoylation occurs at the PM [ 16 ] . Cells expressing α i2 or sα i2 were metabolically labeled with 3H-palmitate or 3H-myristate.

  • Like other proteins modified by palmitoylation, the Src family kinase Fyn is found localized in RAFTs, a membrane microdomain fraction enriched in signaling molecules that can be isolated by sucrose gradient fractionation.

  • On the other hand, when the first ten amino acids of α i2 are fused to GFP to create α i2 (1-10)-GFP, fluorescence is detected strongly at the PM (Figure 5C), indicating the N-terminus of α i2 , which contains the sites for myristoylation and palmitoylation [ 14 ] , can be sufficient for directing PM localization of a normally cytosolic protein.

  • Most of the CPKs contain fatty-acylation sites, including those for myristoylation and palmitoylation, which seem to be necessary for targeting to membranes and for protein-protein interactions [ 67].


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