Example sentences for: pai-

How can you use “pai-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is clear that the smad7 gene expression is regulated by TGFβ in a Smad3/4-dependent manner [ 32 ] as it was found for the pthrp and the pai-1 gene [ 19 33 ] . However, the Smad3 responsive elements are different.

  • Studies of PAI-deficient or overexpressing mice indicate that PAI-1 regulates the amount of collagen deposition in the lung [ 27].

  • PAI-1 inhibitory activity is expressed as the number of international units of PAs inhibited by PAI-1.

  • The second-order rate constants for the interaction of the fibrosarcoma PAI-1, wtPAI-1 or the indicated mutants with single-chain tPA or uPA were determined in a single-step assay as previously described.

  • These results suggest that the role of the Asp355-Pro357 segment is to stabilize the inhibitory conformation of PAI-1.


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