Words similar to pai
Example sentences for: pai
How can you use “pai” in a sentence? Here are some example sentences to help you improve your vocabulary:
Paramutation has been studied extensively for four maize loci that encode transcriptional regulators of pigment biosynthesis [ 1 ] . Paramutation has also been investigated in the Arabidopsis PAI gene family, at the a1 and chalcone synthase (CHS) transgene loci in petunia, and in a number of other cases [ 2 3 4 ] . The Arabidopsis resistance gene BAL/CPR1 displays a related form of epigenetic instability [ 5 6 ] . Interactions resembling paramutation also occur among non-allelic transgene loci with DNA sequence homology.
PAI conceived of the study and participated in its design and coordination.
In contrast, in the PAI gene family, combining the master locus (WS ecotype PAI1/PAI4 ) with a non-allelic singlet target locus possessing 100% sequence identity (Columbia PAI2 ) resulted in methylation after two generations of heterozygous contact, and methylation became more pronounced after another two generations [ 12 ] . Likewise, in the petunia CHS gene family, interaction between an epiallele of the direct-repeat locus, CHS41, with two types of target loci, either an unlinked inverted repeat locus or a more naïve allele of CHS41, was initially additive and only became suppressive in the second generation [ 4 10 ] .
It is informative to compare the epigenetic interactions of the 35S:GFP-COP1 transgenes with those of the PAI (trans)genes, the only other well-characterized system in Arabidopsis [ 12 ] . Both gene sets consist of relatively simple repeat structures and singlet loci, which reside in essentially single-copy environments of Arabidopsis ( [ 27 ] and unpublished observations).
In contrast, a trans-methylated singlet PAI2 gene did not trans-methylate a naive allelic PAI2 gene within three generations [ 12 ] . Additional experimentation may eventually provide an answer to the question of what controls the efficiency of such epigenetic interactions.
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