Example sentences for: p-associated

How can you use “p-associated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As Pcu3p-associated ubiquitin ligase activity was not described before, we first needed to determine which of the fourteen different ubiquitin-conjugating enzymes (UBCs) present in the fission yeast genome associate with the RING domain protein Pip1p, an essential cofactor of cullin ubiquitin ligases [ 7, 28, 29, 30].

  • 2A), Pcu3p-associated ubiquitin ligase activity recovered from this mutant showed a much more dramatic increase (Fig.

  • Thus, CSN deficiency appears to stimulate Pcu3p-associated ubiquitin ligase activity in vitro . A similar stimulation was obtained for substrate-specific polyubiquitylation of phosphorylated Rum1p by SCF Poppurified from csn5 mutants (unpublished observation).

  • Further experiments are required to determine whether recombinant Csn5p or purified CSN complex can inhibit Pcu3p-associated ubiquitin ligase activity.


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