Example sentences for: oxysterol

How can you use “oxysterol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In these proteins, the GOLD domain co-occurs with lipid-, sterol- or fatty acid-binding domains such as PH [ 20, 21], Sec14p [ 22], FYVE [ 23], oxysterol binding- and acyl CoA-binding domains, suggesting that these proteins may interact with membranes.

  • These compounds can activate some nuclear receptors including steroidogenic factor 1 [ 44 ] and LXR, which may be partially responsible for their biological activities [ 45 46 ] . Cholesterol oxides are inhibitors of HMG-CoA reductase, the key enzyme of cholesterol biosynthesis pathway [ 47 ] . The ability to bind to an intracellular receptor, oxysterol binding protein, may be responsible for their inhibition of cholesterol biosynthesis [ 48 49 ] . It should be noted that addition of cholesterol does not prevent cholesterol oxide induced cell death, which leads to the suggestion that inhibition of cholesterol synthesis is not the cause of cholesterol oxide induced PCD [ 50 51 ] . The critical events that result in cholesterol oxide induced cytotoxicity remain to be determined.

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