Example sentences for: oxoguanine

How can you use “oxoguanine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Negative controls were carried out without primary antibodies and with primary antibodies preabsorbed (100-fold molar excess, 2 h, 25 C) with an 8-oxoguanine oligonucleotide (3850-100-01; Trevigen), human recombinant p53 (Santa Cruz Biotechnology, Santa Cruz, CA), Bcl-2 peptide (amino acids 41-54; StressGen), or recombinant polymerase β (Trevigen).

  • Alterations in p53 were related to accretions of apoptotic/internucleosomal DNA cleavage sites [ 13 ] , the oxidative DNA stress marker 8-oxoguanine [ 14 ] , the survival protein Bcl-2 [ 15 ] , and base-excision repair polymerase β [ 16 ] . Corpora lutea were evaluated for progesterone and steroidogenic cell and vascular compositions.

  • Results of this study indicate that in underfed ewes p53, Bcl-2, and polymerase β are up-regulated in fetal oogonia containing elevated contents of 8-oxoguanine.

  • Levels of p53 in maternal oocytes were not altered overall (irrespective of follicular classification) by undernutrition (Figure 2); and therefore, we did not monitor the inductive damage (8-oxoguanine) or response survival (Bcl-2)/repair (polymerase β) markers.

  • Measures were made on twenty germ cells (within a respective section) per fetus for each analytical procedure: p53, apoptotic DNA fragmentation, 8-oxoguanine, Bcl-2, and polymerase β.


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