Words similar to overexpress
Example sentences for: overexpress
How can you use “overexpress” in a sentence? Here are some example sentences to help you improve your vocabulary:
MCF-7 cells are known to have fewer than five copies of the Her2/neu gene, whereas HCC1954 cells overexpress the protein because of gene amplification [ 40 41 ] . Her2/neu protein levels were determined with a Her2/neu ELISA kit (Oncogene) in accordance with the manufacturer's instructions.
MCF7/ADR cells have been demonstrated to overexpress MDR1/P-gp, as well as the GSTπ and MRP genes.
Localization of this protein to the nucleus also mirrors that of endogenous PP1α in vivo . When using this system to forcibly overexpress 6His-HA-PP1α, there is a concomitant decrease in endogenous PP1α levels, suggesting the existence of an autoregulatory mechanism by which PP1α protein levels remain constant.
Previously, we generated transgenic mice that overexpress the homeobox transcription factor Hoxc-8 in the thoracic region, where Hoxc-8 is normally expressed ( [ 1 ] and unpublished results).
A reporter construct containing the basal promoter of the rat RIIβ 5'-flanking region (-394 to -123) upstream of a CAT-reporter gene (pCATbasic; Promega, Madison, WI) was used for assaying RIIβ promoter activity [ 18 ] . Expression vectors for USF1, USF2a and USF2b inserted 3' of the CMV promoter in pCR™3 (Invitrogen, Groningen, The Netherlands) were used to overexpress USF isoforms [ 12 ] . C/EBPβ LAP (full-length) and LIP (DNA-binding domain) expression vectors created in pCMV™3 (Stratagene, La Jolla, CA) were appreciated gifts from Dr. Shizua Akira (Hyogo College of Medicine, Hyogo, Japan).
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