Example sentences for: over-expression

How can you use “over-expression” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, over-expression of βγ prevents ALLN-induced juxtanuclear accumulations of α i2 but not sα i2 (Figure 9).

  • Orthologs of Arabidopsis flowering genes have been identified in several other species, including pea and snapdragon [ 3 ] , rice [ 4 ] , maize [ 5 ] , pine [ 6 ] and ryegrass [ 7 ] . In addition, transformation of one plant species with constructs resulting in the over-expression of flowering genes from another plant species resulted in effects on flowering dynamics [ 3 7 8 ] . This indicates that the function of several flowering genes is conserved between plant species.

  • Cdc5 is required for full activation of the Dbf2-Mob1 protein kinase complex [ 15 16 17 ] , and has been proposed to impinge on the MEN both upstream and downstream of Tem1 [ 15 16 17 18 ] . During exit from mitosis, Cdc5 is required for Clb2 destruction, and similar to over-expression of Cdc14 [ 3 ] , induction of Cdc5 triggers precocious Clb2 degradation in pre-anaphase cells [ 19 20 ] . In addition to its role in exit from mitosis, Cdc5 has other functions during mitosis in budding yeast.

  • For example, through the use of STAT5-/- mice, Ihle et al have been able to identify those IL-2 target genes that require STAT5 [ 56 57 ] . Similar approaches with mutant signaling proteins, knockouts, or over-expression systems enable such dissection of the signal transduction pathways leading to specific target genes.

  • It has been shown that engineered over-expression of wild-type p53 in vitro causes inhibition of MGMT transcription in human tumor cells [ 29 ] . Abundant over-expression of wild-type p53, owing to their stage of origin, is a characteristic feature of GCTs [ 30 ] . A possibility also exists that the MGMT expression may, in general, be down regulated in tumors arising from embryonic-type cells.


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