Example sentences for: outbred

How can you use “outbred” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Gly583Cys mutation in Abcg5 is likely to have originated in the original outbred Wistar colony bred in Kyoto (from which WKY was subsequently derived), which has been widely employed as a normotensive control in experimental studies of hypertension.

  • This Swiss-Webster outbred mouse strain utilized in this study has proven to be a valuable model for investigating the efficacy of both anabolic and anti-resorptive therapies for the treatment of osteoporosis.

  • To analyze the impact of intra-patient variability (tissue heterogeneity), inter-patient variability (polymorphic noise in outbred populations), and the effect of sample mixing on the sensitivity of detection of gene expression differences between patient groups, we conducted a series of individual and mixed profiling (Table 1).

  • The SHR strain was derived by selective inbreeding from the Kyoto outbred Wistar colony, and both SHR and SHRSP, as well as WKY strains have been maintained over many generations through brother-sister matings http://rgd.mcw.edu/tools/strains [ 43 44 ] . Healthy WKA and GH rat strains were also generated from outbred Wistar rat strains, but these strains were isolated independently in Japan and New Zealand, respectively (and maintained at other sites as well).

  • While analysts have predicted that very high polymorphism densities will be required for association mapping in mixed or outbred populations [see for example reference [ 7 ] ], promising results have been obtained using genome scans of 600-1200 STRPs in isolated populations where levels of linkage disequilibrium are particularly high [ 8 9 10 ] . In this manuscript we describe the development of two new 10 cM human STRP Screening Sets (Sets 12 and 52) which when combined provide average STRP spacing of 4.8 cM.


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