Example sentences for: outbred

How can you use “outbred” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A skin air sac model was used to compare the virulence of isolate CS101 and paired isogenic mutants [ 9 ] . Briefly an air- and liquid-tight connective tissue pouch was generated on the back of female, six week old, outbred CD1 mice (Charles River, Portage, MI) by slow dermal injection of 0.9 mL of air via an 0.4 mm needle on a 1.0 mL syringe.

  • To analyze the impact of intra-patient variability (tissue heterogeneity), inter-patient variability (polymorphic noise in outbred populations), and the effect of sample mixing on the sensitivity of detection of gene expression differences between patient groups, we conducted a series of individual and mixed profiling (Table 1).

  • Consistent with this interpretation, Eggan et al have recently shown that viable offspring are more efficiently produced through tetraploid-mediated cloning from outbred ES cell line compared to inbred ES cell lines [ 14 ] . We, therefore, believed it likely that aggregation-compatible hprt negative ES cells could be generated by targeted mutation of the hprt gene in R1 ES cells.

  • Other investigators described differences of the same order of magnitude between mouse strains in expression of transgenes encoding α1-antitrypsin [ 1 ] , interleukin-12 [ 2 ] , and human endostatin [ 3 ] . These differences in transgene expression between inbred species may have clinical implications, as differences between inbred strains are considered to reflect differences between individuals of an outbred species.

  • This can be understood by considering the facts that the human population is highly outbred, and L1 elements are preferentially cis -acting [ 24 27 ] . Progenitor elements for L1-TDs must be transpositionally competent and thus are likely to be relatively young.


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