Example sentences for: induces

How can you use “induces” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Upon stimulation, a cellular signal induces a conformational change in the integrin cytoplasmic domain that propagates to the extracellular domain.

  • Although it has been shown that CPT at higher concentrations induces cell cycle arrest in proliferating dermal fibroblasts [ 26], it is unlikely that the inhibition of collagen production was related to cell cycle arrest, because our experiments were performed with confluent, serum-starved cells.

  • As summarized in Figure 1, PH-20 induces the expression of proapoptotic p53 and WOX1 [ 9 10 ] and downregulates antiapoptotic matrix inter-α-inhibitor [ 9 ] , thereby enhancing TNF susceptibility in L929 cells.

  • Nonetheless, E2F is inactivated and/or downregulated upon progression to S phase, a regulatory feature that appears critical as E2F overexpression or ectopic activation induces apoptosis both in mammalian cells and in flies [ 12 ] [ 13 ] [ 14 ] [ 15 ] . Inactivation of the DNA-binding activity of E2F-1 by the cyclin A/Cdk complex has been shown to be critical for proper S phase progression [ 16 ] . In mammalian cells, E2F-1 is also subject to proteasome-mediated degradation [ 17 ] [ 18 ] [ 19 ] and recent evidence indicates that E2F-1 degradation occurs in S phase [ 20 ] . Control of E2F-1 stability has also been linked to its association with the F-box protein Skp2 [ 20 ] but this has not been tied to a specific phase of the cell cycle.

  • TGF-β expression is closely associated with an increase in wall shear stress [ 30 31 ] and with different forms of fluid shear stress [ 32 ] , and its function is modulated by variety of factors [ 14 ] . For example, TGF-β1 is secreted in an inactive precursor and requires furin-mediated maturation [ 33 ] . TGF-β1 in turn induces expression of furin.


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