Words similar to inactivating

Example sentences for: inactivating

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In the absence of a method such as this for either removing or inactivating unused OCP, nonspecific background amplification can occur [ 13 ] . Sequencing of misamplification products (data not shown, [ 14 ] ) has revealed that misamplification products produced in the absence of ligase usually consist of a short OCP-derived sequence immediately flanked by primer sequences.
The pattern of such promoter methylation has been noted to be non-random in various tumor types, while certain genes are commonly methylated in diverse tumor types [ 10 11 ] . The extent of aberrant promoter hypermethylation and its association with loss of gene function in cancer suggests that CpG island methylation is an important mechanism in inactivating tumor suppressor genes (TSGs).
Some tumours therefore amplify the Mdm2 gene as a means of inactivating p53.
Three independent mouse lines carrying inactivating Pten mutations have been made [ 23, 24, 25].
A nonrandom pattern of promoter hypermethylation has been noted in specific genes in specific tumor types, although some genes are commonly methylated in diverse tumors [ 3 4 ] . The extent of aberrant promoter hypermethylation and its association with loss of gene function in cancer suggests that CpG island methylation is an important mechanism in inactivating tumor suppressor genes (TSGs).