Example sentences for: improvementin

How can you use “improvementin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Both in animal and human studies of heart failure, β-adrenergicblockade intervention appears to have beneficial effects on cardiacmyocyte function [ 1 23 24 ] . Of particularimportance, studies using carvedilol have shown remarkable improvementsin cardiac performance [ 12 13 15 16 ] andreduction in mortality in humans [ 17 ] .We have previously shown that propranolol, a nonselective β-blocker,is cardioprotective and prevents the development of heart failurein turkeys when given concurrently with furazolidone [ 21 ] . Similarly, carteolol, a nonselective β-blocker,resulted in improvement in ejection fraction, reduction in ventricularvolumes, an increase in developed pressure as well as an increasein rate of survival in our turkey model [ 18 ] . Improvementin cardiac function was associated with cellular remodeling of cardiacmyocytes.

  • In vivo contractile performance of the heart was assessed bythe determination of fractional shortening of the left ventricle.As shown in Table 1and Figure 1, fractional shortening was increasedby 32 and 45% in DCM 1 and DCM 20 animals, respectively,compared to non-treated DCM animals (DCM 0 ). Comparedwith baseline values at the time of randomization, the improvementin fractional shortening was of 57% in DCM 1 and 65% inDCM 20 . Associated with improved cardiac function wasa reduction in the incidence of apoptotic nuclei (see below).

  • The data presented suggest that attenuation of apoptosis mayunderlie the beneficial effect of β-blockade on ventricular function,and that the inhibition of apoptosis can possibly lead to improvementin ventricular function.

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