Example sentences for: impinge

How can you use “impinge” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The fact that you are an office of only 10 people, and Lothario now finds himself too busy for some tasks, means the involvement has begun to impinge on the workplace.

  • Cdc5 is required for full activation of the Dbf2-Mob1 protein kinase complex [ 15 16 17 ] , and has been proposed to impinge on the MEN both upstream and downstream of Tem1 [ 15 16 17 18 ] . During exit from mitosis, Cdc5 is required for Clb2 destruction, and similar to over-expression of Cdc14 [ 3 ] , induction of Cdc5 triggers precocious Clb2 degradation in pre-anaphase cells [ 19 20 ] . In addition to its role in exit from mitosis, Cdc5 has other functions during mitosis in budding yeast.

  • Biochemical and cell biological experiments indicate that Net1 acts as part of a complex named RENT that tethers Cdc14 to the nucleolus and inhibits Cdc14 phosphatase activity, and that CDC15 and TEM1 are required for the release of Cdc14 from Net1 at the end of mitosis [ 15 16 17 43 ] . Consistent with this notion, both net1 tab 2-1(which encodes a mutant version of Net1 with presumably reduced affinity for Cdc14) and CDC14 TAB 6-1(which encodes a mutant version of Cdc14 with reduced affinity for Tab2/Net1) bypass cdc15Δ [ 15 18 ] . Both net1 tab 2-1and CDC14 TAB 6-1impinge directly on mitotic exit, suggesting that other TAB genes may encode physiological regulators and effectors of the Mitotic Exit Network.

  • The embryonic stage upon which diapause is supposed to impinge is, however, unclear.

  • Although deregulated HER-2 / neu activity can strongly stimulate cytoplasmic signalling pathways, which in turn impinge on c- myc at multiple levels causing its deregulated expression [ 46 ] , this scenario does not appear to be active in NNBC because the recurrence rate of 22 c- myc and HER-2 / neu coamplified patients was only 9%.


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