Example sentences for: impairing

How can you use “impairing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Earlier studies describing the underlying molecular mechanisms involved in the HIV-1 inhibitory effect of the candidate microbicide CAP indicated that this compound remains bound to HIV-1, impairing virus infectivity by blockade of binding sites for cellular coreceptors CXCR4 and CCR5 [ 8 ] . Results reported here further extend these findings and show that: 1) there is synergism between sCD4 and CAP for inhibition of virus infectivity; 2) CAP binding to HIV-1 leads to conformational changes in viral envelope glycoproteins resulting in the expression of functionally inert six-helix bundle structures.

  • The results indicate that in rat pancreatic β-cells, PMA modulates insulin secretion through a mixed mechanism: increases insulin secretion by activation of PKC, and meanwhile decrease insulin secretion by impairing β-cell excitability in a PKC-independent manner.

  • This inability to dimerize substantially decreases the enzymes affinity for DNA consequently impairing its polymerase and RNase H activities.

  • Fine particles absorb and scatter light, impairing visibility.

  • These results provide a novel insight of modulation mechanism of insulin secretion by PMA, increases insulin secretion by activation of PKC, and meanwhile decrease insulin secretion by impairing β-cell excitability in a PKC-independent manner in rat pancreatic β-cells.


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