Example sentences for: impaired

How can you use “impaired” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although radiation treatment alone impaired tumor growth in both intervention and regression trials, it produced no significant extension of survival time in either trial (Figure 4).

  • Analysis of DNA synthesis in the mutant embryos indicated that cell proliferation was impaired, suggesting that BRCA1 may paradoxically play a positive role in the regulation of embryonic cell growth [ 29].

  • They also demonstrated that children with BMI exceeding the 85 thpercentile are at increased risk of diabetes or impaired fasting glucose, odds ratio of 5.1 with 95% coefficient interval 1.5, 17.

  • In induced models of autoimmunity, the CD28-B7 interaction has been shown to regulate disease susceptibility by rendering autoreactive T cells anergic, or alternatively by upregulating the threshold for autoreactive T-cell activation [ 30 ] . Furthermore, we previously showed that impaired Fas-mediated activation-induced cell death (AICD) of autoreactive T-helper-1 cells may be responsible for the development of PGIA [ 20 ] . Therefore, AICD and/or T-cell anergy, but not the CD4 +CD25 +regulatory T cells, may be responsible for deletion or inactivation of autoreactive T cells in autoimmune arthritis.

  • If agencies cannot protect the availability, integrity, and, in some cases, the confidentiality, of this information, their ability to carry out their missions will be severely impaired.


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