Example sentences for: immunogenicity

How can you use “immunogenicity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A candidate vaccine comprised of a fusion protein based on two antigens has been selected and is currently in pharmaceutical development under the sponsorship of this project, with the goal of evaluating the safety and immunogenicity in humans.

  • Overall maximum titer levels vary, but the difference in immunogenicity between B. lentus subtilisin and BPN' Y217L has been seen in three separate guinea pig studies.

  • Different serogroups have vastly different frequencies among pneumococci isolated from carriage [12,15,16,17] and otitis media [12,18]; for example, serogroups 4 and 18 and the non-vaccine serogroups are isolated far less commonly than several of the other pneumococcal types identified in Figure 1. One could postulate that these differences in frequency of carriage are offset by differences in immunogenicity; however, there is little evidence that serotypes 4 or 18C are more immunogenic than other, far more common serotypes [4,15].

  • DNA- and peptide-based vaccines have become popular due to the comparative ease of construction, the circumvention of potential safety issues around attenuated organisms, and for their potentially enhanced immunogenicity compared to heat-killed and subunit vaccines [ 20 21 22 ] . DNA vaccines have the added attraction of efficiently priming both humoral and cytotoxic cell responses, a property largely lacking in subunit and attenuated organism vaccines.

  • Animal models can play an essential role in guiding preclinical vaccine development, including in studies of preclinical vaccine safety, vaccine toxicity, and vaccine immunogenicity.

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