Example sentences for: immunodeficiencies

How can you use “immunodeficiencies” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This could be a chance event, or it may result from selection for certain X-linked alleles during embryonic development, as has been described in carriers of X-linked immunodeficiencies [ 17].

  • This could be a chance event, or may result from selection for certain X-linked alleles during embryonic development, as has been described in carriers of X-linked immunodeficiencies [ 17].

  • The importance of the Tec kinases in antigen receptor signaling was first demonstrated by the observation that mutations in BTK result in the human disease X-linked agammaglobulinemia (XLA) and the murine counterpart X-linked immunodeficiency ( xid ). These severe B cell immunodeficiencies are characterized by diminished numbers of mature B cells and reduced immunoglobulin levels associated with impaired PLC-γ activation and Ca ++mobilization in response to surface IgM stimulation (sIgM) [ 8, 9, 10, 11].

  • They usually produce inaparent infection or transient immune compromise in otherwise healthy hosts but are able to cause life-threatening primary or reactivated infections in individuals with congenital or acquired T-cell immunodeficiencies [ 7 8 9 10 11 12 13 14 15 ] . The spectrum of diseases caused by lymphotropic herpesviruses is well documented in patients undergoing bone marrow transplantation (BMT) [ 8 9 10 11 ] or organ transplantation [ 12 13 ] and in individuals infected with human immunodeficiency virus (HIV) [ 14 15 ] . In patients undergoing conventional anticancer therapy without BMT, the data focusing on EBV, CMV or HHV-6 infection are scarcely documented and mostly reported as individual cases [ 16 17 18 19 ] . With combined diagnostic approach of serology and viral DNA detection we performed a prospective study of children undergoing non-BMT therapy for cancer to demostrate the incidence of LH infections.


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