Words similar to imatinib

Example sentences for: imatinib

How can you use “imatinib” in a sentence? Here are some example sentences to help you improve your vocabulary:

Similar mutations in the homologous residues of the kinase domains of PDGFRA (T674I) and KIT (T670I) account for imatinib resistance in some patients with hypereosinophilic syndrome and gastrointestinal stromal cell tumors, respectively [4,12].
Imatinib induces complete remission in most patients with CML in stable phase [1], and also has activity in CML that has progressed to blast crisis [2].
This was first appreciated in patients with CML treated with imatinib whose tumors developed resistance, and has been most extensively studied in that context.
0020075), the initial identification three years ago of resistance mutations against imatinib led to the rapid development of alternative kinase inhibitors that work even against tumors with the resistance mutation.
Although imatinib inhibits different kinases in various diseases (BCR-ABL in CML, KIT or PDGFR-alpha in gastrointestinal stromal tumors [GISTs], and PDGFR-alpha in hypereosinophilic syndrome [HES]) (reviewed in [14]), some tumors that become refractory to treatment with imatinib appear to have analogous secondary mutations in the kinase-coding domain of the genes encoding these three enzymes.