Example sentences for: ihc

How can you use “ihc” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The efficacy and specificity of OPN, TSP-1 and TYRP-1 antibodies in IHC was tested by analysis of frozen tissue xenografts of known target gene expression [ 2 5 ] . Positive cytoplasmic staining was detected with the OPN antibody in nine of 26 (35%) primary breast carcinomas with nodal metastases.

  • Clinically, TYRP-1 is thought to be important as a melanoma antigen that is highly antigenic to cytotoxic T cells, providing a potential target for melanoma vaccine development [ 16 ] . TYRP-1 appears to be less expressed in advanced primary lesions and metastases of human cutaneous melanoma and uveal melanoma [ 32 ] . Primary melanoma samples express TYRP-1 transcripts at higher levels than melanoma metastases [ 33 ] , and IHC analysis of malignant melanocytic lesions has shown that the invasive cells of primary melanomas are TYRP-1-negative [ 34 ] .

  • The utility of these antibodies for IHC in paraffin-embedded specimens is being investigated.

  • Four pairs of additional formalin-fixed, paraffin-embedded (FFPE) specimens of primary infiltrating ductal carcinomas and of matched nodal metastasis were also used for IHC only (total of 76 samples for IHC).

  • Thus, the anti-NKB antibody (IHC 7357) showed the following crossreactivities: 100% for NKB, 2% for physalaemin, 1% for eledoisin, 0.6% for kassinin, 0.2% for substance P, 0.1% for NKA and 0% for neuropeptide K. Moreover, in the nuclei of the human brainstem in which NKB was observed, the density of the immunoreactivity for NKB was lesser than that found in the same nuclei for NKA (see and compare Figs.


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