Example sentences for: i-igf-ii

How can you use “i-igf-ii” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Expression of the ribozyme targeted against the M6P/IGF2 receptor in MCF-7 cells resulted in down-regulation of M6P/IGF2R expression, as measured by RT-PCR, and M6P/IGF2R function, indicated by a decrease in internalization of 125I-IGF-II, and β-glucuronidase binding and endocytosis.

  • To determine the effect of the ribozyme on the functional activity of M6P/IGF2R, the binding and internalization of exogenous 125I-IGF-II was measured in cells infected with Ad-GFP/Rz-IGF2R or Ad-GFP.

  • 4A, cells infected with Ad-GFP/Rz-IGF2R had a corresponding reduction of ~40% in 125I-IGF-II internalization when compared with control cells (infected with Ad-GFP).

  • Specific internalized 125I-IGF-II was calculated by subtracting the counts of samples with excessive unlabeled IGF-II from that without unlabeled IGF-II, and normalized to protein content.


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