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Example sentences for: delg

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Expression profiles from the mutant clonal cell line (1159del28) and three additional clonal mutant MeCP2 expressing cell lines (T158M, 803delG, R168X) were compared to the baseline expression profiles.
Clonal cell lines with the mutant MECP2 allele on the active X chromosome were derived from lymphoblastoid cell lines (LCLs) from four females with clinically diagnosed Rett syndrome and known mutations (T158M, 803delG, R168X) [ 10 ] and 1159del28 (unpublished) using the technique described above.
We, therefore, extended the microarray analyses to lymphoblastoid cell lines (LCLs) and studied four clonal mutant MeCP2 (T158M, 803delG, R168X and 1159del28) expressing and one clonal (1159del28) and four completely skewed (R106W, R255X, 803delG, 803delG) wild-type MeCP2 expressing LCLs.
Cell clones expressing an allele with a truncating mutation (FB 705delG, FB 1155del32, LCL R168X), do not produce a normal sized MECP2 protein.
The number of genes with increased (+) and decreased (-) levels of expression in mutant MeCP2 over wild-type expressing clones differed among the fibroblast strains studied (R106W: 889+, 3056-; R306C: 1700+, 1435-; 705delG: 1160+, 1240-; 1155del32: 2996+, 1235-).