Example sentences for: degranulation

How can you use “degranulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, despite this activity, there was no high affinity IgE receptor (FcεRI)-induced degranulation.

  • In humans, antigen-specific anaphylactic reactivity is thought to be mediated solely (or primarily) by IgE antibodies, whereas it has long been known that either IgE or IgG1 antibodies can mediate anaphylaxis in mice (reviewed in [ 14 15 ] and [ 17 ] ). However, it has been reported that IgG1-dependent anaphylaxis in the mouse is associated with substantially less histological evidence of mast cell degranulation than is observed in IgE-dependent anaphylaxis in that species [ 17 ] . In neither of the models of "autoimmunity" that we have studied (i.e.

  • , EAE, T1DM in NOD mice) was anaphylaxis associated with histological evidence of substantial mast cell degranulation [ 14 ] (data not shown).

  • The phenomenon of allograft rejection and IL-2-induced tumor rejection may not only be characterized by the induction of a vigorous inflammatory response but share a common cytotoxic effector mechanism (NK/T-cell degranulation) that is ultimately responsible for direct tissue destruction.

  • Furthermore, degranulation of platelets and neutrophils may contribute to the elevation of serum levels of MMP-2 and MMP-9 seen in the patients, and may be an explanation for the high baseline level in the serum [ 52, 53].


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