Example sentences for: defect

How can you use “defect” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • First, redundancy in methyl-CpG binding proteins that recruit transcriptional silencing complexes may mask the effects of MeCP2 deficiency; for example, MBD1, MBD2 or Kaiso, may complement the defect in the cell types we studied.

  • To determine if activated AKT was increased in tumors that had a Pten defect, these sections were stained using an antibody that specifically detects AKT1 phosphorylated at Ser 473 (and AKT2 and AKT3 phosphorylated at equivalent sites).

  • They found a decrease in total (apical + basolateral) bile acid uptake compared to normal controls [ 12 ] and hypothesized that bile acid malabsorption in cystic fibrosis was due to a primary mucosal defect although they had not specifically studied apical, Na +-dependent absorption.

  • Whether this disease is caused by a primary defect in the nerve or the muscle remains unclear.

  • Such an apoptotic defect could account for the increasing intensity of Ogg1 staining, following accumulated levels of 8-OH-dG adducts with longer duration of diabetes.


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