Example sentences for: deacetylase

How can you use “deacetylase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • SAHA was reported to be a histone deacetylase inhibitor and caused accumulation of hyperacetylated histone H4 in murine erythroleukemia [ 17].

  • It was reported that some agents, e.g. histone deacetylase inhibitors [ 14 ] or DNA methylation inhibitors [ 15 ] , can rescue the IFNg inducibility of MHCII in cultured tumor cells.

  • 4B) were examined to identify the potency of SAHA as a histone deacetylase inhibitor on mammary epithelial cells.

  • The resulting retinoblastoma protein (Rb)-E2F interaction not only blocks transcriptional activation by E2F, but also forms an active transcriptional repressor complex at the promoter of cell cycle genes that can block transcription by recruiting histone deacetylase (HDAC) and remodeling chromatin [ 11, 12, 13, 14].

  • We also found evidence that promoter methylation inactivates gene expression in CC and exposure to methylation and/or histone deacetylase (HDAC)-inhibiting agents reactivate the gene expression.


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