Example sentences for: als

How can you use “als” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 1 and 1q12, respectively [ 8 ] . These loci overlap with the genomic regions containing the genes for amyotrophic lateral sclerosis 5 (ALS5) and limb girdle muscular dystrophy 1B (LGMD1B), respectively [ 22 23 ] . We characterized these tropomodulin genomic loci for use in mutational analysis.

  • We also used the monoclonal antibody α-ALS (mab D4) and a polyclonal serum α-Dα2, both directed against α-like ligand-binding subunits of the Drosophila nAChR [ 25, 28].

  • However, dramatic reduction of copper in SOD1 by knocking out the copper chaperon for SOD1 (CCS), or by mutating the copper chelating residues, did not affect ALS progression in vivo [ 36 48 ] . Therefore, the role of copper-mediated oxidative damage remains unclear [ 49 50 ] .

  • Interestingly, accumulation of ceramides and cholesterol esters has been observed in ALS patients and mice [ 67 ] , which could be associated with peroxisomal proliferation.

  • Amyotrophic lateral sclerosis (ALS) is an age-dependent neurodegenerative disease that causes progressive motoneuron degeneration, skeletal muscle atrophy, paralysis and death [ 1 2 3 ] . Although clinically indistinguishable, the majority of cases are sporadic (SALS) and approximately 10 % are due to inherited causes (familial ALS or FALS).


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