Example sentences for: alpha-

How can you use “alpha-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Between 1966 and 2001, there were 188 published cardiovascular randomized controlled trials related to the treatment of hypertension with the use of peripheral alpha-1 antagonists.

  • The human alpha-2C receptor, which has a DESSAAAE motif with only two hydroxyl residues, does not undergo down-regulation.

  • A motif with four hydroxyl amino acid residues in an acidic environment appears to be important for down-regulation of the alpha-2C adrenergic receptor.

  • The human alpha-2C receptor, by contrast, has a DESSAAAE sequence in the same region [Figure 2; [ 22 ] ]. Thus, it is possible that the lack of desensitization and perhaps also down-regulation of the human alpha-2C receptor is due to the fact that there are only two hydroxyl residues in the DESSAAAE motif rather than the four hydroxyl residues in the alpha-2A EESSSSD motif.

  • 113 nM) and similar to the previously reported K d of 0.056 nM for the wild-type alpha-2 receptor for [ 3H]rauwolscine in NaPO 4 buffer [ 23 ] . Inhibition experiments with [ 3H]rauwolscine indicated that the affinity of norepinephrine for the mutated receptors was approximately two-fold higher (lower K d value) than for wild-type receptor (Figure 3).


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