Words similar to allergen
Example sentences for: allergen
How can you use “allergen” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cigarette smoke has also been considered a major player in the pathogenesis of asthma and as a trigger for acute symptoms [ 2 ] . Exposure to cigarette smoke activates an inflammatory cascade in the airway epithelium resulting in the production of a number of potent cytokines and chemokines, with accompanying damage to the lung epithelium, increased permeability, and recruitment of macrophages and neutrophils to the airway [ 3 ] . Even brief exposure to cigarette smoke has been shown to increase expression of IL-8 in primary cultures of human bronchial epithelial cells (HBEs) in the presence of dust mite allergen [ 4 ] . Increased release of the chemokine IL-8 has also been shown for cultured HBEs exposed to cigarette smoke extract (CSE) [ 5 6 ] and diesel exhaust particles [ 7 ] . However, the precise molecular events that bring about these intracellular changes and acute inflammation in lung epithelial cells are not well understood.
In contrast to clusters A and B, the genes in cluster D were downregulated in response to the allergen challenge (Figure 1b).
Investigators have treated patients with related molecules, either peptides derived from the allergen itself, or much smaller peptides produced synthetically.
Indeed, there is already excellent evidence that injection of peptides derived from the cat allergen Fel d 1, which give T cell responses, can be used for immunotherapy [18].
The largest number of differentially expressed cDNA elements (127) was seen 4 h after the allergen challenge, with fewer observed at 18 h (46 cDNA elements) or 24 h after challenge (31 cDNA elements).
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