Words similar to alleles
Example sentences for: alleles
How can you use “alleles” in a sentence? Here are some example sentences to help you improve your vocabulary:
Tests of gene essentiality in Candida necessitate serial disruption of both alleles using two different selection markers.
As noted by Doherty and Zinkernagel [ 4 ] , simple dominance for resistance to each of several diseases can create allele-specific overdominance for total fitness, if different alleles confer resistance to different diseases [ 10 31 ] . For these reasons, our results, while relevant to the longstanding debate over the relative importance of various kinds of balancing selection in maintaining MHC diversity [ 32 ] , raise doubts about only one of several lines of evidence for the overdominance hypothesis.
Experimental studies [ 21 22 ] have shown that the CYP17 polymorphism in the 5'-flanking region of the gene does not influence binding to Sp1, as previously conjectured [ 1 20 ] . Nonetheless, studies in both premenopausal women and postmenopausal women have found that those with A2 alleles have higher circulating levels of steroid hormones.
It can also accommodate overdominance of the resistant alleles ( a > 1; b > d ; c > d ), in which each heterozygote does better than either corresponding homozygote, and underdominance, in which each heterozygote does worse than either corresponding homozygote ( a < 1; b < 1; c < d ). In this model, susceptibility and resistance are relative and simply refer respectively to lower and higher probabilities of favorable disease course, given infection.
Multiple strains were generated that were homozygous for each of the F, M and S electrophoretic alleles of Pgm, by appropriate crosses to a third chromosome balancer stock.
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