Example sentences for: akt

How can you use “akt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The presence of areas unstained with antibody specific for phosphorylated AKT suggests that additional factors other than Pten may influence the activation of AKT.

  • The significance of HGF/SF as a marker of poor prognosis might also be associated with its effects on acquired resistance to anti-cancer drugs [ 35 36 ] . HGF/SF protects cancer cells from DNA-damaging chemotherapy agents through pathways involving signaling from Met to phosphoinositide 3-kinase and c-Akt [ 29 ] . Human breast cancer cells, preincubated with HGF/SF and then exposed to Adriamycin, exhibit an altered pattern of gene expression compared with cells treated with Adriamycin alone.

  • Activated AKT was more abundant in tumors that were Wnt-1 TG, Pten +/- with LOH, as has been shown for uterine tumors in Pten heterozygous mice (KP, RP, submitted).

  • This glioma is deficient in PTEN and shows constitutive activation of Akt, which can be inactivated by re-introduction of PTEN [ 47 ] .

  • Substrates of AKT include glycogen synthase kinase 3 (GSK3), p70/S6 kinase, BAD, Caspase 9, 4E-BP1, IκB kinase α and members of the Forkhead transcription family [reviewed in ref.


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