Example sentences for: agonist

How can you use “agonist” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To test whether similar phenomena occur in mammalian cells with Hh protein and agonist, we generated stable cell lines expressing two epitope-tagged proteins, Ptc coupled to green fluorescent protein, Ptc-GFP, and Smo coupled to a fragment of influenza hemagglutinin, HA-Smo.

  • Two families of small peptides binding to the human thrombopoietin receptor (TPOR) were isolated that competed with the natural ligand TPO [ 34 ] . The peptide with the highest affinity was subsequently dimerized and shown to function as a potent TPO agonist in vivo . Recently, a small, non-peptide organic molecule binding to one chain of the EPO receptor was multimerized and shown to mimic the biological activities of the EPO [ 35 ] .

  • Agonist 1 was not toxic at 20 μM.

  • Depolarization propagation was also inhibited by muscimol, a GABA A receptor agonist, in a dose dependent manner, and inhibition was reversed by bicuculline, a GABA A receptor antagonist.

  • Thus, the present study was designed to achieve the following goals; (1) to describe the activation profiles of a set of opioid ligands not previously defined in an isolated cell system expressing only μ opioid receptor, and (2) to compare the efficacies of these drugs to the known, highly efficacious μ receptor agonist, fentanyl, the common opioid analgesic morphine and to the endogenous opioid ligand β-endorphin.


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